› 2khc

Solution NMR

Bruno RRM3+

Released:
DOI: 10.2210/pdb2khc/pdb
PDB entry 2khc coloured by chain, ensemble of 10 models, front view.
PDB entry 2khc coloured by chain, ensemble of 10 models, side view.
PDB entry 2khc coloured by chain, ensemble of 10 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
Bruno protein contains an expanded RNA recognition motif.
Lyon AM, Reveal BS, Macdonald PM, Hoffman DW
Biochemistry 48 12202-12 (2009)
PMID: 19919093

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127576 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RRM domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 118 amino acids
Theoretical weight: 12.3 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: O18409 (Residues: 684-801; Coverage: 15%)
Gene names: CG31762, aret, bru1, bruno
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Translational control in oocyte development.
Richter et al. (2011)
2 more

3 mentions without citation

ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.
Gal et al. (2016)
2 more