2k8v

Solution NMR

Solution structure of Oxidised ERp18

Released:

Function and Biology Details

Reaction catalysed:
2 glutathione + protein-disulfide = glutathione disulfide + protein-dithiol
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein 12 Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95881 (Residues: 24-172; Coverage: 100%)
Gene names: TLP19, TXNDC12, UNQ713/PRO1376
Sequence domains: Thioredoxin-like
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Chemical shifts: BMR7430   BMR15964  
Expression system: Escherichia coli