› 2jsw

Solution NMR

Solution Structure of the R13 Domain of Talin

Released:
DOI: 10.2210/pdb2jsw/pdb
PDB entry 2jsw coloured by chain, ensemble of 20 models, front view.
PDB entry 2jsw coloured by chain, ensemble of 20 models, side view.
PDB entry 2jsw coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
The structure of the C-terminal actin-binding domain of talin.
Gingras AR, Bate N, Goult BT, Hazelwood L, Canestrelli I, Grossmann JG, Liu H, Putz NS, Roberts GC, Volkmann N, Hanein D, Barsukov IL, Critchley DR
EMBO J 27 458-69 (2008)
PMID: 18157087

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Talin-1 Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 19.38 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26039 (Residues: 2300-2482; Coverage: 7%)
Gene names: Tln, Tln1
Sequence domains: I/LWEQ domain
Structure domains: I/LWEQ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

35 review citations

Environmental sensing through focal adhesions.
Geiger et al. (2009)
34 more

13 mentions without citation

Considering protonation as a posttranslational modification regulating protein structure and function.
Schönichen et al. (2013)
12 more