Solution NMR

Solution structure of the ERCC1 central domain


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
DNA excision repair protein ERCC-1 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P07992 (Residues: 96-219; Coverage: 42%)
Gene name: ERCC1
Sequence domains: Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: simulated annealing
Chemical shifts: BMR15240  
Expression system: Escherichia coli