X-ray diffraction
2.45Å resolution

Structure of UMP kinase from Pyrococcus furiosus complexed with UTP

Source organism: Pyrococcus furiosus
Entry authors: Marco-Marin C, Rubio V

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Uridylate kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 227 amino acids
Theoretical weight: 24.76 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q8U122 (Residues: 1-225; Coverage: 100%)
Gene names: PF1407, pyrH
Sequence domains: Amino acid kinase family
Structure domains: Acetylglutamate kinase-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: I23
Unit cell:
a: 144.943Å b: 144.943Å c: 144.943Å
α: 90° β: 90° γ: 90°
R R work R free
0.209 0.209 0.254
Expression system: Escherichia coli BL21(DE3)