Structure analysis

Structure of deoxyadenosine kinase from M.mycoides with bound dATP

X-ray diffraction
2.7Å resolution
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 18600 Å2
Buried surface area: 3900 Å2
Dissociation area: 1,000 Å2
Dissociation energy (ΔGdiss): 7 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): -35 kcal/mol
Symmetry number: 2
Assembly 2
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Multimeric state: homo dimer
Accessible surface area: 18900 Å2
Buried surface area: 3900 Å2
Dissociation area: 950 Å2
Dissociation energy (ΔGdiss): 5 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): -28 kcal/mol
Symmetry number: 2
Assembly 3
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Multimeric state: homo dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Chains: A, B, C, D, E, F
Length: 206 amino acids
Theoretical weight: 24.43 KDa
Source organism: Mycoplasma mycoides subsp. mycoides SC
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q93IG4 (Residues: 1-205; Coverage: 100%)
Gene name: dGUOK
Pfam: Deoxynucleoside kinase
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases

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