X-ray diffraction
1.73Å resolution

blLAP in Complex with Microginin FR1


Function and Biology Details

Reactions catalysed:
Release of N-terminal proline from a peptide.
Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.
An (L-cysteinylglycine)-S-conjugate + H(2)O = an L-cysteine-S-conjugate + glycine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cytosol aminopeptidase Chain: A
Molecule details ›
Chain: A
Length: 487 amino acids
Theoretical weight: 52.96 KDa
Source organism: Bos taurus
  • Canonical: P00727 (Residues: 33-519; Coverage: 94%)
Gene name: LAP3
Sequence domains: Cytosol aminopeptidase family, catalytic domain
Structure domains:
Molecule details ›
Chain: D
Length: 4 amino acids
Theoretical weight: 543 Da
Source organism: Microcystis sp.

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P6322
Unit cell:
a: 129.982Å b: 129.982Å c: 120.813Å
α: 90° β: 90° γ: 120°
R R work R free
0.146 0.145 0.173