X-ray diffraction
1.57Å resolution

Structural of ABDH, a beta-diketone hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 bound to (S)-3-oxocyclohexyl acetic acid


Function and Biology Details

Reaction catalysed:
Nonane-4,6-dione + H(2)O = pentan-2-one + butanoate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Enoyl-CoA hydratase/carnithine racemase Chains: A, B
Molecule details ›
Chains: A, B
Length: 263 amino acids
Theoretical weight: 30.07 KDa
Source organism: Nostoc sp. PCC 7120 = FACHB-418
Expression system: Escherichia coli BL21
  • Canonical: Q8YNV6 (Residues: 1-253; Coverage: 100%)
Gene name: alr4455
Sequence domains: Enoyl-CoA hydratase/isomerase
Structure domains: 2-enoyl-CoA Hydratase; Chain A, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P63
Unit cell:
a: 80.387Å b: 80.387Å c: 125.882Å
α: 90° β: 90° γ: 120°
R R work R free
0.14 0.138 0.17
Expression system: Escherichia coli BL21