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Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex

Source organisms:
Biochemical function: not assigned
Biological process: immune response
Cellular component: extracellular space

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF07654
Domain description: Immunoglobulin C1-set domain
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
The deposited structure of PDB entry 2j4w contains 1 copy of Pfam domain PF07654 (Immunoglobulin C1-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain B [auth H].
The deposited structure of PDB entry 2j4w contains 1 copy of Pfam domain PF07654 (Immunoglobulin C1-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain C [auth L].

PF07686
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
The deposited structure of PDB entry 2j4w contains 1 copy of Pfam domain PF07686 (Immunoglobulin V-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain B [auth H].
The deposited structure of PDB entry 2j4w contains 1 copy of Pfam domain PF07686 (Immunoglobulin V-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain C [auth L].

PF02430
Domain description: Apical membrane antigen 1
Occurring in:
  1. Apical membrane antigen 1
The deposited structure of PDB entry 2j4w contains 1 copy of Pfam domain PF02430 (Apical membrane antigen 1) in Apical membrane antigen 1. Showing 1 copy in chain A [auth D].

InterPro InterPro annotations
IPR003298
Domain description: Apical membrane antigen 1
Occurring in:
  1. Apical membrane antigen 1
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
IPR024056
Domain description: Apical membrane antigen 1 domain superfamily
Occurring in:
  1. Apical membrane antigen 1
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Ig-like domain-containing protein

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
The deposited structure of PDB entry 2j4w contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Ig-like domain-containing protein. Showing 2 copies in chain B [auth H].
The deposited structure of PDB entry 2j4w contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Ig-like domain-containing protein. Showing 2 copies in chain C [auth L].
SCOP SCOP annotations
48942
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
The deposited structure of PDB entry 2j4w contains 1 copy of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in Ig-like domain-containing protein. Showing 1 copy in chain B [auth H].
The deposited structure of PDB entry 2j4w contains 1 copy of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in Ig-like domain-containing protein. Showing 1 copy in chain C [auth L].
48727
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. Ig-like domain-containing protein
  2. Ig-like domain-containing protein
The deposited structure of PDB entry 2j4w contains 1 copy of SCOP domain 48727 (V set domains (antibody variable domain-like)) in Ig-like domain-containing protein. Showing 1 copy in chain B [auth H].
The deposited structure of PDB entry 2j4w contains 1 copy of SCOP domain 48727 (V set domains (antibody variable domain-like)) in Ig-like domain-containing protein. Showing 1 copy in chain C [auth L].
82911
Class: Small proteins
Fold: Apical membrane antigen 1
Superfamily: Apical membrane antigen 1
Occurring in:
  1. Apical membrane antigen 1
The deposited structure of PDB entry 2j4w contains 1 copy of SCOP domain 82911 (Apical membrane antigen 1) in Apical membrane antigen 1. Showing 1 copy in chain A [auth D].

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