Structure analysis

Shikimate kinase from Mycobacterium tuberculosis in complex with ADP, open LID (conf. B)

X-ray diffraction
1.35Å resolution
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 10000 Å2
Buried surface area: 700 Å2
Dissociation area: 50 Å2
Dissociation energy (ΔGdiss): 6 kcal/mol
Dissociation entropy (TΔSdiss): -1 kcal/mol
Interface energy (ΔGint): -8 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 184 amino acids
Theoretical weight: 19.68 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPY3 (Residues: 1-176; Coverage: 100%)
Gene names: MTCY159.17, Rv2539c, aroK
Pfam: Shikimate kinase
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases
SCOP: Shikimate kinase (AroK)

Search similar proteins