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12th PDZ domain of Multiple PDZ Domain Protein MPDZ

X-ray diffraction
2.15Å resolution
PDB entry 2iwp coloured by chain, front view.
PDB entry 2iwp coloured by chain, side view.
PDB entry 2iwp coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Multiple PDZ domain protein
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Multimeric state: homo dimer
Accessible surface area: 9421.41 Å2
Buried surface area: 2361.38 Å2
Dissociation area: 1,180.69 Å2
Dissociation energy (ΔGdiss): 16.94 kcal/mol
Dissociation entropy (TΔSdiss): 10.58 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-131186

Macromolecules

Multiple PDZ domain protein
Chains: A, B
Length: 120 amino acids
Theoretical weight: 12.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75970 (Residues: 1858-1951; Coverage: 5%)
Gene names: MPDZ, MUPP1
Pfam: PDZ domain
InterPro:
CATH: Pdz3 Domain
Multiple PDZ domain protein in PDB entry 2iwp, assembly 1, front view.
Multiple PDZ domain protein in PDB entry 2iwp, assembly 1, side view.
Multiple PDZ domain protein in PDB entry 2iwp, assembly 1, top view.
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