2iq1

X-ray diffraction
2.25Å resolution

Function and Biology Details

Reaction catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein phosphatase 1K, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 30.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8N3J5 (Residues: 89-351; Coverage: 71%)
Gene names: PP2CM, PPM1K
Sequence domains: Protein phosphatase 2C
Structure domains: PPM-type phosphatase domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P212121
Unit cell:
a: 59.442Å b: 69.406Å c: 77.401Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.239
Expression system: Escherichia coli BL21(DE3)