2ii0

X-ray diffraction
2.02Å resolution

Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-170560 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Son of sevenless homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 490 amino acids
Theoretical weight: 57.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07889 (Residues: 564-1049; Coverage: 37%)
Gene name: SOS1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: C2
Unit cell:
a: 82.771Å b: 66.799Å c: 119.653Å
α: 90° β: 108.91° γ: 90°
R-values:
R R work R free
0.218 0.218 0.248
Expression system: Escherichia coli