› 2igz

Solution NMR

NMR structure of the sterol-dependent antifungal antibiotic bacillomycin Lc

Released:
DOI: 10.2210/pdb2igz/pdb
PDB entry 2igz coloured by chain, ensemble of 19 models, front view.
PDB entry 2igz coloured by chain, ensemble of 19 models, side view.
PDB entry 2igz coloured by chain, ensemble of 19 models, top view.
Source organism: Bacillus subtilis
Primary publication:
NMR structure determination of a synthetic analogue of bacillomycin Lc reveals the strategic role of L-Asn1 in the natural iturinic antibiotics.
Volpon L, Tsan P, Majer Z, Vass E, Hollósi M, Noguéra V, Lancelin JM, Besson F
Spectrochim Acta A Mol Biomol Spectrosc 67 1374-81 (2007)
PMID: 17129757

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162755 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BACILLOMYCIN L-3 Chain: A
Molecule details ›
Chain: A
Length: 8 amino acids
Theoretical weight: 1.05 KDa
Source organism: Bacillus subtilis
Expression system: Not provided

Ligands and Environments

No bound ligands
3 modified residues:
Ligand DTY 1 x DTY
Ligand DSG 1 x DSG
Ligand DSN 1 x DSN

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

2 review citations

Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics.
Raaijmakers et al. (2010)
1 more

1 mention without citation

LPD-12: a promising lipopeptide to control COVID-19.
Chowdhury et al. (2021)