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Crystal Structure of the Lingo-1 Ectodomain

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF13855
Domain description: Leucine rich repeat
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
The deposited structure of PDB entry 2id5 contains 36 copies of Pfam domain PF13855 (Leucine rich repeat) in Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. Showing 9 copies in chain B.

PF07679
Domain description: Immunoglobulin I-set domain
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
The deposited structure of PDB entry 2id5 contains 4 copies of Pfam domain PF07679 (Immunoglobulin I-set domain) in Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR003591
Domain description: Leucine-rich repeat, typical subtype
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR013098
Domain description: Immunoglobulin I-set
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR026906
Domain description: BspA-type LRR region
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
IPR000372
Domain description: Leucine-rich repeat N-terminal domain
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
The deposited structure of PDB entry 2id5 contains 4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. Showing 1 copy in chain B.
3.80.10.10
Class: Alpha Beta
Architecture: Alpha-Beta Horseshoe
Topology: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
Homology: Ribonuclease Inhibitor
Occurring in:
  1. Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
The deposited structure of PDB entry 2id5 contains 4 copies of CATH domain 3.80.10.10 (Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)) in Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1. Showing 1 copy in chain B.

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