2id5

X-ray diffraction
2.7Å resolution

Crystal Structure of the Lingo-1 Ectodomain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 477 amino acids
Theoretical weight: 54.27 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q96FE5 (Residues: 40-516; Coverage: 82%)
Gene names: LERN1, LINGO1, LRRN6A, UNQ201/PRO227
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21212
Unit cell:
a: 201.517Å b: 149.72Å c: 157.486Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.255
Expression system: Cricetulus griseus