Structure analysis

Crystal Structure of human DEAD-box RNA helicase DDX3X

X-ray diffraction
2.2Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 20200 Å2
Buried surface area: 500 Å2
Dissociation area: 250 Å2
Dissociation energy (ΔGdiss): 3 kcal/mol
Dissociation entropy (TΔSdiss): 4 kcal/mol
Interface energy (ΔGint): -4 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 417 amino acids
Theoretical weight: 47.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00571 (Residues: 168-582; Coverage: 63%)
Gene names: DBX, DDX3, DDX3X
Pfam:
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases

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