2hxh

Electron Microscopy
11Å resolution

KIF1A head-microtubule complex structure in adp-form

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Tubulin alpha-1A chain Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 50.12 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P02550 (Residues: 1-451; Coverage: 100%)
Gene name: TUBA1A
Sequence domains:
Tubulin beta chain Chain: B
Molecule details ›
Chain: B
Length: 445 amino acids
Theoretical weight: 49.91 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P02554 (Residues: 1-445; Coverage: 100%)
Sequence domains:
Kinesin-like protein KIF1A Chain: C
Molecule details ›
Chain: C
Length: 394 amino acids
Theoretical weight: 44.3 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P33173 (Residues: 3-355; Coverage: 21%)
Gene names: Atsv, Kif1, Kif1a
Sequence domains: Kinesin motor domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 11Å
Expression system: Escherichia coli BL21(DE3)