X-ray diffraction
1.8Å resolution

Structure of PIN domain of human SMG6


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Telomerase-binding protein EST1A Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 181 amino acids
Theoretical weight: 20.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: Q86US8 (Residues: 1239-1419; Coverage: 13%)
Gene names: C17orf31, EST1A, KIAA0732, SMG6
Sequence domains: PIN domain
Structure domains: 5'-nuclease

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 36.879Å b: 71.216Å c: 181.273Å
α: 90° β: 90° γ: 90°
R R work R free
0.222 0.222 0.267
Expression system: Escherichia coli BL21