2hwk

X-ray diffraction
2.45Å resolution

Crystal Structure of Venezuelan Equine Encephalitis Alphavirus nsP2 Protease Domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
helicase nsP2 Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 36.24 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WIJ1 (Residues: 1003-1322; Coverage: 17%)
Gene name: NS
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CAMD BEAMLINE GCPCC
Spacegroup: P212121
Unit cell:
a: 47.47Å b: 72.58Å c: 106.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.192 0.242
Expression system: Escherichia coli