Function and Biology Details
Reaction catalysed:
tRNA uridine(55) = tRNA pseudouridine(55)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ribosomal protein eL8/Nhp2 family
- Large ribosomal subunit protein eL8, archaea
- Ribosomal protein eL30-like superfamily
- H/ACA ribonucleoprotein complex, subunit Nop10
- PUA domain
- tRNA pseudouridine synthase B family
- Dyskerin-like
- Large ribosomal subunit protein eL8-like, conserved site
12 more domains
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-181659 (preferred)
Entry contents:
4 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (5 distinct):
Probable tRNA pseudouridine synthase B
Molecule details ›
Chain: A
Length: 346 amino acids
Theoretical weight: 39.45 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 346 amino acids
Theoretical weight: 39.45 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q7LWY0 (Residues: 1-340; Coverage: 100%)
Sequence domains:
- DKCLD (NUC011) domain
- TruB family pseudouridylate synthase (N terminal domain)
- tRNA pseudouridylate synthase B C-terminal domain
- PUA domain
Small nucleolar rnp gar1-like protein
Molecule details ›
Chain: B
Length: 104 amino acids
Theoretical weight: 12.34 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
Sequence domains: Gar1/Naf1 RNA binding region
Structure domains: Probable tRNA pseudouridine synthase domain
Length: 104 amino acids
Theoretical weight: 12.34 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
- Canonical: Q8U029 (Residues: 1-104; Coverage: 100%)
Sequence domains: Gar1/Naf1 RNA binding region
Structure domains: Probable tRNA pseudouridine synthase domain
Ribosome biogenesis protein Nop10
Molecule details ›
Chain: C
Length: 60 amino acids
Theoretical weight: 7.21 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
Sequence domains: Nucleolar RNA-binding protein, Nop10p family
Structure domains: H/ACA ribonucleoprotein complex, subunit Nop10
Length: 60 amino acids
Theoretical weight: 7.21 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
- Canonical: Q8U1R4 (Residues: 1-60; Coverage: 100%)
Sequence domains: Nucleolar RNA-binding protein, Nop10p family
Structure domains: H/ACA ribonucleoprotein complex, subunit Nop10
Large ribosomal subunit protein eL8
Molecule details ›
Chain: D
Length: 130 amino acids
Theoretical weight: 14.31 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Structure domains: 60s Ribosomal Protein L30; Chain: A;
Length: 130 amino acids
Theoretical weight: 14.31 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
- Canonical: Q8U160 (Residues: 1-123; Coverage: 100%)
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Structure domains: 60s Ribosomal Protein L30; Chain: A;
