2huu

X-ray diffraction
2.1Å resolution

Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase in complex with alanine

Released:
Source organism: Aedes aegypti
Entry authors: Han Q, Robinson H, Gao YG, Vogelaar N, Wilson SR, Rizzi M, Li J

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alanine--glyoxylate aminotransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 43.39 KDa
Source organism: Aedes aegypti
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q3LSM4 (Residues: 1-393; Coverage: 100%)
Gene names: AAEL010480, AGT
Sequence domains: Aminotransferase class-V
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: R3
Unit cell:
a: 137.116Å b: 137.116Å c: 120.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.152 0.15 0.195
Expression system: Spodoptera frugiperda