2huo

X-ray diffraction
2Å resolution

Crystal structure of mouse myo-inositol oxygenase in complex with substrate

Released:
Source organism: Mus musculus
Entry authors: Brown PM, Caradoc-Davies TT, Dickson JMJ, Cooper GJS, Loomes KM, Baker EN

Function and Biology Details

Reaction catalysed:
Myo-inositol + O(2) = D-glucuronate + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inositol oxygenase Chain: A
Molecule details ›
Chain: A
Length: 289 amino acids
Theoretical weight: 33.52 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9QXN5 (Residues: 1-285; Coverage: 100%)
Gene names: Aldrl6, Miox, Rsor
Sequence domains: Myo-inositol oxygenase

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29, SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 44.602Å b: 77.202Å c: 85.397Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.204 0.256
Expression system: Escherichia coli