2hg4

X-ray diffraction
2.73Å resolution

Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-deoxyerythronolide-B synthase EryA3, modules 5 and 6 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 917 amino acids
Theoretical weight: 97.98 KDa
Source organism: Saccharopolyspora erythraea
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q03133 (Residues: 1-896, 897-917; Coverage: 29%)
Gene name: eryA
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2
Unit cell:
a: 305.258Å b: 150.149Å c: 184.378Å
α: 90° β: 110.03° γ: 90°
R-values:
R R work R free
0.218 0.216 0.255
Expression system: Escherichia coli BL21