X-ray diffraction
2.6Å resolution

Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP


Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
EphB2/CTF2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 286 amino acids
Theoretical weight: 32.29 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P54763 (Residues: 614-898; Coverage: 29%)
Gene names: Ephb2, Epth3, Nuk, Sek3
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 60.798Å b: 98.304Å c: 114.168Å
α: 90° β: 90.18° γ: 90°
R R work R free
0.205 0.205 0.26
Expression system: Escherichia coli