2hci

X-ray diffraction
1.81Å resolution

Structure of Human Mip-3a Chemokine

Released:
Source organism: Homo sapiens
Primary publication:
Structure of human MIP-3alpha chemokine.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62 631-4 (2006)
PMID: 16820679

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 20 Chains: A, B
Molecule details ›
Chains: A, B
Length: 69 amino acids
Theoretical weight: 7.91 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P78556 (Residues: 27-95; Coverage: 99%)
Gene names: CCL20, LARC, MIP3A, SCYA20
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: I4
Unit cell:
a: 83.991Å b: 83.991Å c: 57.221Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.206 0.254
Expression system: Not provided