2h8k

X-ray diffraction
3.2Å resolution

Human Sulfotranferase SULT1C3 in complex with PAP

Released:

Function and Biology Details

Reaction catalysed:
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sulfotransferase 1C3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 306 amino acids
Theoretical weight: 36.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6IMI6 (Residues: 1-304; Coverage: 100%)
Gene name: SULT1C3
Sequence domains: Sulfotransferase domain
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2221
Unit cell:
a: 87.161Å b: 108.717Å c: 136.925Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.294 0.292 0.342
Expression system: Escherichia coli BL21(DE3)