› › Structure analysis

Src kinase in complex with a quinazoline inhibitor

X-ray diffraction
2.2Å resolution
PDB 2h8h coloured by chain and viewed from the front.
PDB 2h8h coloured by chain and viewed from the side.
PDB 2h8h coloured by chain and viewed from the top.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly

Macromolecules

Proto-oncogene tyrosine-protein kinase Src
Chain: A
Length: 535 amino acids
Theoretical weight: 59.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P12931 (Residues: 2-536; Coverage: 100%)
Gene names: SRC, SRC1
Pfam:
InterPro:
CATH:
SCOP:
PDB 2h8h contains 1 copy of Proto-oncogene tyrosine-protein kinase Src in assembly 1. This protein is highlighted and viewed from the front.
PDB 2h8h contains 1 copy of Proto-oncogene tyrosine-protein kinase Src in assembly 1. This protein is highlighted and viewed from the side.
PDB 2h8h contains 1 copy of Proto-oncogene tyrosine-protein kinase Src in assembly 1. This protein is highlighted and viewed from the top.
Molecule details ›

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