› 2gwe

X-ray diffraction
2.2Å resolution

Crystal structure of D(G4T4G4) with six quadruplexes in the asymmetric unit.

Released:
DOI: 10.2210/pdb2gwe/pdb
PDB 2gwe coloured by chain and viewed from the front.
PDB 2gwe coloured by chain and viewed from the side.
PDB 2gwe coloured by chain and viewed from the top.
Source organism: Synthetic construct
Entry authors: Lee MPH, Haider S, Parkinson GN, Neidle S

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3' Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 12 nucleotides
Theoretical weight: 3.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand K 30 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 47.645Å b: 78.881Å c: 97.011Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 not available 0.318
Expression system: Not provided

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