› 2gqp

X-ray diffraction
1.5Å resolution

N-Domain Of Grp94 In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine

Released:
DOI: 10.2210/pdb2gqp/pdb
PDB entry 2gqp coloured by chain, front view.
PDB entry 2gqp coloured by chain, side view.
PDB entry 2gqp coloured by chain, top view.
Source organism: Canis lupus familiaris
Entry authors: Immormino RM, Gewirth DT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endoplasmin Chains: A, B
Molecule details ›
Chains: A, B
Length: 236 amino acids
Theoretical weight: 26.51 KDa
Source organism: Canis lupus familiaris
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P41148 (Residues: 69-337; Coverage: 30%)
Gene names: GRP94, HSP90B1, HSPC4, TRA1
Sequence domains: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Structure domains: Histidine kinase-like ATPase, C-terminal domain

Ligands and Environments

4 bound ligands:
Ligand MG 1 x MG
Ligand PA7 2 x PA7
Ligand PG4 7 x PG4
Ligand 1PE 1 x 1PE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P212121
Unit cell:
a: 65.69Å b: 84.84Å c: 95.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.235
Expression system: Escherichia coli BL21(DE3)

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