Structure analysis

Structure of QacR Multidrug Transcriptional Regulator Bound to Bivalent Diamidine Berenil

X-ray diffraction
2.9Å resolution
Source organism: Staphylococcus aureus
Assemblies composition:
homo dimer (preferred)
homo hexadecamer
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 17815.66 Å2
Buried surface area: 4902.88 Å2
Dissociation area: 1,863.35 Å2
Dissociation energy (ΔGdiss): 7.34 kcal/mol
Dissociation entropy (TΔSdiss): 12.67 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-140958
Assembly 2
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Multimeric state: homo dimer
Accessible surface area: 17389.59 Å2
Buried surface area: 3886.26 Å2
Dissociation area: 1,532.01 Å2
Dissociation energy (ΔGdiss): 10.53 kcal/mol
Dissociation entropy (TΔSdiss): 12.95 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-140958
Assembly 3
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Multimeric state: homo hexadecamer
Accessible surface area: 125942.9 Å2
Buried surface area: 50029.78 Å2
Dissociation area: 4,826.11 Å2
Dissociation energy (ΔGdiss): 16.57 kcal/mol
Dissociation entropy (TΔSdiss): 18.53 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-140957
Assembly 4
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Multimeric state: homo hexadecamer
Accessible surface area: 121244.25 Å2
Buried surface area: 54728.43 Å2
Dissociation area: 2,603.7 Å2
Dissociation energy (ΔGdiss): 10.83 kcal/mol
Dissociation entropy (TΔSdiss): 17.37 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-140957

Macromolecules

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