› 2gby

X-ray diffraction
2.9Å resolution

Structure of QacR Multidrug Transcriptional Regulator Bound to Bivalent Diamidine Berenil

Released:
DOI: 10.2210/pdb2gby/pdb
PDB 2gby coloured by chain and viewed from the front.
PDB 2gby coloured by chain and viewed from the side.
PDB 2gby coloured by chain and viewed from the top.
Source organism: Staphylococcus aureus
Entry author: Schuman JT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexadecamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator QacR Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 194 amino acids
Theoretical weight: 22.98 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A0N4 (Residues: 1-188; Coverage: 100%)
Gene names: SAP100B_005, SAP104C_022, qacR
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 11 x SO4
Ligand BRN 1 x BRN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P42212
Unit cell:
a: 171.34Å b: 171.34Å c: 94.53Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.249 0.29
Expression system: Escherichia coli

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