2g0e

X-ray diffraction
2.88Å resolution

Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs

Released:
Source organism: Staphylococcus haemolyticus
Entry author: Schuman JT

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexadecamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator QacR Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 188 amino acids
Theoretical weight: 22.15 KDa
Source organism: Staphylococcus haemolyticus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A0N5 (Residues: 1-188; Coverage: 100%)
Gene name: qacR
Sequence domains: QacR-like protein, C-terminal region
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P42212
Unit cell:
a: 170.47Å b: 170.47Å c: 94.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.299
Expression system: Escherichia coli