X-ray diffraction
1.76Å resolution

Urate oxidase from aspergillus flavus complexed with allantoin


Function and Biology Details

Reaction catalysed:
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Biochemical function:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Uricase Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 34.2 KDa
Source organism: Aspergillus flavus
Expression system: Saccharomyces cerevisiae
  • Canonical: Q00511 (Residues: 2-302; Coverage: 100%)
Gene names: Uox, uaZ
Sequence domains: Uricase
Structure domains: Urate Oxidase;

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: I222
Unit cell:
a: 80.364Å b: 96.086Å c: 105.368Å
α: 90° β: 90° γ: 90°
R R work R free
0.207 not available not available
Expression system: Saccharomyces cerevisiae