› 2ful

X-ray diffraction
1.5Å resolution

Crystal Structure of the C-terminal Domain of S. cerevisiae eIF5

Released:
DOI: 10.2210/pdb2ful/pdb
PDB entry 2ful coloured by chain, front view.
PDB entry 2ful coloured by chain, side view.
PDB entry 2ful coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of the C-terminal domain of S.cerevisiae eIF5.
Wei Z, Xue Y, Xu H, Gong W
J Mol Biol 359 1-9 (2006)
PMID: 16616930

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153652 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 5 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 177 amino acids
Theoretical weight: 20.41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P38431 (Residues: 241-405; Coverage: 41%)
Gene names: TIF5, YP3085.05, YPR041W
Sequence domains: eIF4-gamma/eIF5/eIF2-epsilon
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

1 bound ligand:
Ligand SO4 20 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P1
Unit cell:
a: 44.849Å b: 64.536Å c: 108.916Å
α: 88.6° β: 86.57° γ: 74.93°
R-values:
R R work R free
0.178 0.177 0.205
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation.
Hinnebusch AG. (2017)
2 more

8 mentions without citation

Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.
Dever et al. (2016)
7 more