Function and Biology

Structural Model for the Large Subunit of the Mammalian Mitochondrial Ribosome

Source organism: Bos taurus
Biochemical function: structural constituent of ribosome
Biological process: translation
Cellular component: ribosome

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00542
Domain description: Ribosomal protein L7/L12 C-terminal domain
Occurring in:
  1. Large ribosomal subunit protein bL12m
The deposited structure of PDB entry 2ftc contains 2 copies of Pfam domain PF00542 (Ribosomal protein L7/L12 C-terminal domain) in Large ribosomal subunit protein bL12m. Showing 1 copy in chain F [auth E].

PF16320
Domain description: Ribosomal protein L7/L12 dimerisation domain
Occurring in:
  1. Large ribosomal subunit protein bL12m
The deposited structure of PDB entry 2ftc contains 2 copies of Pfam domain PF16320 (Ribosomal protein L7/L12 dimerisation domain) in Large ribosomal subunit protein bL12m. Showing 1 copy in chain F [auth E].

PF00468
Domain description: Ribosomal protein L34
Occurring in:
  1. Large ribosomal subunit protein bL34m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00468 (Ribosomal protein L34) in Large ribosomal subunit protein bL34m. Showing 1 copy in chain R [auth Q].

PF00471
Domain description: Ribosomal protein L33
Occurring in:
  1. Large ribosomal subunit protein bL33m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00471 (Ribosomal protein L33) in Large ribosomal subunit protein bL33m. Showing 1 copy in chain Q [auth P].

PF01016
Domain description: Ribosomal L27 protein
Occurring in:
  1. Large ribosomal subunit protein bL27m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF01016 (Ribosomal L27 protein) in Large ribosomal subunit protein bL27m. Showing 1 copy in chain P [auth O].

PF17136
Domain description: Ribosomal proteins 50S L24/mitochondrial 39S L24
Occurring in:
  1. Large ribosomal subunit protein uL24m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF17136 (Ribosomal proteins 50S L24/mitochondrial 39S L24) in Large ribosomal subunit protein uL24m. Showing 1 copy in chain O [auth N].

PF00467
Domain description: KOW motif
Occurring in:
  1. Large ribosomal subunit protein uL24m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00467 (KOW motif) in Large ribosomal subunit protein uL24m. Showing 1 copy in chain O [auth N].

PF00237
Domain description: Ribosomal protein L22p/L17e
Occurring in:
  1. Large ribosomal subunit protein uL22m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00237 (Ribosomal protein L22p/L17e) in Large ribosomal subunit protein uL22m. Showing 1 copy in chain N [auth M].

PF00453
Domain description: Ribosomal protein L20
Occurring in:
  1. Large ribosomal subunit protein bL20m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00453 (Ribosomal protein L20) in Large ribosomal subunit protein bL20m. Showing 1 copy in chain M [auth L].

PF01245
Domain description: Ribosomal protein L19
Occurring in:
  1. Large ribosomal subunit protein bL19m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF01245 (Ribosomal protein L19) in Large ribosomal subunit protein bL19m. Showing 1 copy in chain L [auth K].

PF01196
Domain description: Ribosomal protein L17
Occurring in:
  1. Large ribosomal subunit protein bL17m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF01196 (Ribosomal protein L17) in Large ribosomal subunit protein bL17m. Showing 1 copy in chain K [auth J].

PF00252
Domain description: Ribosomal protein L16p/L10e
Occurring in:
  1. Large ribosomal subunit protein uL16m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00252 (Ribosomal protein L16p/L10e) in Large ribosomal subunit protein uL16m. Showing 1 copy in chain J [auth I].

PF00572
Domain description: Ribosomal protein L13
Occurring in:
  1. Large ribosomal subunit protein uL13m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00572 (Ribosomal protein L13) in Large ribosomal subunit protein uL13m. Showing 1 copy in chain I [auth H].

PF00298
Domain description: Ribosomal protein L11, RNA binding domain
Occurring in:
  1. Large ribosomal subunit protein uL11m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00298 (Ribosomal protein L11, RNA binding domain) in Large ribosomal subunit protein uL11m. Showing 1 copy in chain H [auth G].

PF03946
Domain description: Ribosomal protein L11, N-terminal domain
Occurring in:
  1. Large ribosomal subunit protein uL11m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF03946 (Ribosomal protein L11, N-terminal domain) in Large ribosomal subunit protein uL11m. Showing 1 copy in chain H [auth G].

PF00573
Domain description: Ribosomal protein L4/L1 family
Occurring in:
  1. Large ribosomal subunit protein uL4m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00573 (Ribosomal protein L4/L1 family) in Large ribosomal subunit protein uL4m. Showing 1 copy in chain E [auth D].

PF00297
Domain description: Ribosomal protein L3
Occurring in:
  1. Large ribosomal subunit protein uL3m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00297 (Ribosomal protein L3) in Large ribosomal subunit protein uL3m. Showing 1 copy in chain D [auth C].

PF03947
Domain description: Ribosomal Proteins L2, C-terminal domain
Occurring in:
  1. Large ribosomal subunit protein uL2m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF03947 (Ribosomal Proteins L2, C-terminal domain) in Large ribosomal subunit protein uL2m. Showing 1 copy in chain C [auth B].

PF00181
Domain description: Ribosomal Proteins L2, RNA binding domain
Occurring in:
  1. Large ribosomal subunit protein uL2m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00181 (Ribosomal Proteins L2, RNA binding domain) in Large ribosomal subunit protein uL2m. Showing 1 copy in chain C [auth B].

PF00687
Domain description: Ribosomal protein L1p/L10e family
Occurring in:
  1. Large ribosomal subunit protein uL1m
The deposited structure of PDB entry 2ftc contains 1 copy of Pfam domain PF00687 (Ribosomal protein L1p/L10e family) in Large ribosomal subunit protein uL1m. Showing 1 copy in chain B [auth A].

Rfam RNA family (Rfam)
RF02541
Domain description: Bacterial large subunit ribosomal RNA
Occurring in:
  1. Mitochondrial 16S ribosomal RNA
The deposited structure of PDB entry 2ftc contains 1 copy of Rfam domain RF02541 (Bacterial large subunit ribosomal RNA) in Mitochondrial 16S ribosomal RNA. Showing 1 copy in chain A [auth R].

InterPro InterPro annotations
IPR005813
Domain description: Large ribosomal subunit protein bL20
Occurring in:
  1. Large ribosomal subunit protein bL20m
IPR005822
Domain description: Large ribosomal subunit protein uL13
Occurring in:
  1. Large ribosomal subunit protein uL13m
IPR001684
Domain description: Large ribosomal subunit protein bL27
Occurring in:
  1. Large ribosomal subunit protein bL27m
IPR001857
Domain description: Large ribosomal subunit protein bL19
Occurring in:
  1. Large ribosomal subunit protein bL19m
IPR000114
Domain description: Large ribosomal subunit protein uL16, bacterial-type
Occurring in:
  1. Large ribosomal subunit protein uL16m
IPR000911
Domain description: Ribosomal protein uL11
Occurring in:
  1. Large ribosomal subunit protein uL11m
IPR014719
Domain description: Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like
Occurring in:
  1. Large ribosomal subunit protein bL12m
IPR036235
Domain description: Large ribosomal subunit protein bL12, oligomerization domain superfamily
Occurring in:
  1. Large ribosomal subunit protein bL12m
IPR000206
Domain description: Large ribosomal subunit protein bL12
Occurring in:
  1. Large ribosomal subunit protein bL12m
IPR000456
Domain description: Large ribosomal subunit protein bL17
Occurring in:
  1. Large ribosomal subunit protein bL17m
IPR008991
Domain description: Translation protein SH3-like domain superfamily
Occurring in:
  1. Large ribosomal subunit protein uL2m
  2. Large ribosomal subunit protein bL19m
  3. Large ribosomal subunit protein uL24m
IPR001705
Domain description: Large ribosomal subunit protein bL33
Occurring in:
  1. Large ribosomal subunit protein bL33m
IPR003256
Domain description: Large ribosomal subunit protein uL24
Occurring in:
  1. Large ribosomal subunit protein uL24m
IPR036394
Domain description: Ribosomal protein uL22 superfamily
Occurring in:
  1. Large ribosomal subunit protein uL22m
IPR001063
Domain description: Large ribosomal subunit protein uL22
Occurring in:
  1. Large ribosomal subunit protein uL22m
IPR035566
Domain description: Ribosomal protein bL20, C-terminal
Occurring in:
  1. Large ribosomal subunit protein bL20m
IPR036373
Domain description: Large ribosomal subunit protein bL17 superfamily
Occurring in:
  1. Large ribosomal subunit protein bL17m
IPR036920
Domain description: Large ribosomal subunit protein uL16 superfamily
Occurring in:
  1. Large ribosomal subunit protein uL16m
IPR036899
Domain description: Large ribosomal subunit protein uL13 superfamily
Occurring in:
  1. Large ribosomal subunit protein uL13m
IPR036769
Domain description: Large ribosomal subunit protein uL11, C-terminal domain superfamily
Occurring in:
  1. Large ribosomal subunit protein uL11m
IPR013823
Domain description: Large ribosomal subunit protein bL12, C-terminal
Occurring in:
  1. Large ribosomal subunit protein bL12m
IPR008932
Domain description: Large ribosomal subunit protein bL12, oligomerization
Occurring in:
  1. Large ribosomal subunit protein bL12m
IPR023574
Domain description: Large ribosomal subunit protein uL4 domain superfamily
Occurring in:
  1. Large ribosomal subunit protein uL4m
IPR013005
Domain description: Large ribosomal subunit protein uL4-like
Occurring in:
  1. Large ribosomal subunit protein uL4m
IPR000597
Domain description: Large ribosomal subunit protein uL3
Occurring in:
  1. Large ribosomal subunit protein uL3m
IPR019927
Domain description: Large ribosomal subunit protein uL3, bacterial/organelle-type
Occurring in:
  1. Large ribosomal subunit protein uL3m
IPR022669
Domain description: Large ribosomal subunit protein uL2, C-terminal
Occurring in:
  1. Large ribosomal subunit protein uL2m
IPR014722
Domain description: Large ribosomal subunit protein uL2, domain 2
Occurring in:
  1. Large ribosomal subunit protein uL2m
  2. Large ribosomal subunit protein uL24m
IPR012340
Domain description: Nucleic acid-binding, OB-fold
Occurring in:
  1. Large ribosomal subunit protein uL2m
IPR028364
Domain description: Ribosomal protein uL1/ribosomal biogenesis protein
Occurring in:
  1. Large ribosomal subunit protein uL1m
IPR000271
Domain description: Large ribosomal subunit protein bL34
Occurring in:
  1. Large ribosomal subunit protein bL34m
IPR011332
Domain description: Zinc-binding ribosomal protein
Occurring in:
  1. Large ribosomal subunit protein bL33m
IPR038584
Domain description: Large ribosomal subunit protein bL33 superfamily
Occurring in:
  1. Large ribosomal subunit protein bL33m
IPR041988
Domain description: Large ribosomal subunit protein uL24, KOW domain
Occurring in:
  1. Large ribosomal subunit protein uL24m
IPR005825
Domain description: Large ribosomal subunit protein uL24, conserved site
Occurring in:
  1. Large ribosomal subunit protein uL24m
IPR005824
Domain description: KOW
Occurring in:
  1. Large ribosomal subunit protein uL24m
IPR047867
Domain description: Large ribosomal subunit protein uL22, bacterial/organelle-type
Occurring in:
  1. Large ribosomal subunit protein uL22m
IPR038657
Domain description: Large ribosomal subunit protein bL19 superfamily
Occurring in:
  1. Large ribosomal subunit protein bL19m
IPR016180
Domain description: Large ribosomal subunit protein uL16 domain
Occurring in:
  1. Large ribosomal subunit protein uL16m
IPR047873
Domain description: Large ribosomal subunit protein uL16
Occurring in:
  1. Large ribosomal subunit protein uL16m
IPR023563
Domain description: Large ribosomal subunit protein uL13, conserved site
Occurring in:
  1. Large ribosomal subunit protein uL13m
IPR005823
Domain description: Large ribosomal subunit protein uL13, bacterial-type
Occurring in:
  1. Large ribosomal subunit protein uL13m
IPR020783
Domain description: Large ribosomal subunit protein uL11, C-terminal
Occurring in:
  1. Large ribosomal subunit protein uL11m
IPR020784
Domain description: Large ribosomal subunit protein uL11, N-terminal
Occurring in:
  1. Large ribosomal subunit protein uL11m
IPR036796
Domain description: Large ribosomal subunit protein uL11, N-terminal domain superfamily
Occurring in:
  1. Large ribosomal subunit protein uL11m
IPR006519
Domain description: Large ribosomal subunit protein uL11, bacterial-type
Occurring in:
  1. Large ribosomal subunit protein uL11m
IPR002136
Domain description: Large ribosomal subunit protein uL4
Occurring in:
  1. Large ribosomal subunit protein uL4m
IPR019926
Domain description: Large ribosomal subunit protein uL3, conserved site
Occurring in:
  1. Large ribosomal subunit protein uL3m
IPR009000
Domain description: Translation protein, beta-barrel domain superfamily
Occurring in:
  1. Large ribosomal subunit protein uL3m
IPR022666
Domain description: Large ribosomal subunit protein uL2, RNA-binding domain
Occurring in:
  1. Large ribosomal subunit protein uL2m
IPR002171
Domain description: Large ribosomal subunit protein uL2
Occurring in:
  1. Large ribosomal subunit protein uL2m
IPR016095
Domain description: Large ribosomal subunit protein uL1, 3-layer alpha/beta-sandwich domain
Occurring in:
  1. Large ribosomal subunit protein uL1m
IPR023674
Domain description: Ribosomal protein uL1-like
Occurring in:
  1. Large ribosomal subunit protein uL1m
IPR002143
Domain description: Large ribosomal subunit protein uL1
Occurring in:
  1. Large ribosomal subunit protein uL1m
IPR005879
Domain description: Large ribosomal subunit protein uL1, mitochondrial
Occurring in:
  1. Large ribosomal subunit protein uL1m