2fib

X-ray diffraction
2.01Å resolution

RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) COMPLEXED TO THE PEPTIDE GLY-PRO-ARG-PRO AT PH 6.0

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fibrinogen gamma chain Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 30.24 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02679 (Residues: 169-433; Coverage: 62%)
  • Best match: P02679-2 (Residues: 169-437)
Gene names: FGG, PRO2061
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:
GLY-PRO-ARG-PRO Chain: B
Molecule details ›
Chain: B
Length: 4 amino acids
Theoretical weight: 426 Da

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P21
Unit cell:
a: 37.33Å b: 68.2Å c: 47.6Å
α: 90° β: 105.02° γ: 90°
R-values:
R R work R free
0.186 0.186 0.282
Expression system: Komagataella pastoris