2ffv

X-ray diffraction
2.75Å resolution

Human ppGalNAcT-2 complexed with manganese and UDP

Released:

Function and Biology Details

Reaction catalysed:
UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polypeptide N-acetylgalactosaminyltransferase 2 soluble form Chains: A, B
Molecule details ›
Chains: A, B
Length: 501 amino acids
Theoretical weight: 57.13 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q10471 (Residues: 75-571; Coverage: 87%)
Gene name: GALNT2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P41212
Unit cell:
a: 153.228Å b: 153.228Å c: 110.144Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.286
Expression system: Komagataella pastoris