2ffq

X-ray diffraction
1.78Å resolution

The crystal structure of human neuronal Rab6B in its active GTPgS-bound form

Released:
Source organism: Homo sapiens
Primary publication:
The structure of human neuronal Rab6B in the active and inactive form.
Acta Crystallogr. D Biol. Crystallogr. 62 725-33 (2006)
PMID: 16790928

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-6B Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NRW1 (Residues: 13-174; Coverage: 78%)
Gene name: RAB6B
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 35.885Å b: 60.983Å c: 63.685Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.202
Expression system: Escherichia coli BL21(DE3)