2f3t

X-ray diffraction
3.16Å resolution

Crystal Structure Of E.coli Guanylate Kinase In Complex With Ganciclovir monophosphate

Released:
Source organism: Escherichia coli
Entry authors: Hible G, Cherfils J

Function and Biology Details

Reaction catalysed:
ATP + GMP = ADP + GDP 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Guanylate kinase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 207 amino acids
Theoretical weight: 23.63 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P60546 (Residues: 1-207; Coverage: 100%)
Gene names: JW3623, b3648, gmk, spoR
Sequence domains: Guanylate kinase
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P41212
Unit cell:
a: 107.753Å b: 107.753Å c: 272.663Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.268 0.268 0.29
Expression system: Escherichia coli