2f3m

X-ray diffraction
2.7Å resolution

Structure of human GLUTATHIONE S-TRANSFERASE M1A-1A complexed with 1-(S-(GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXADIENATE ANION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase Mu 1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 218 amino acids
Theoretical weight: 25.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09488 (Residues: 1-218; Coverage: 100%)
Gene names: GST1, GSTM1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GTD 6 x GTD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P1
Unit cell:
a: 51.965Å b: 93.096Å c: 92.998Å
α: 120.53° β: 106.19° γ: 89.97°
R-values:
R R work R free
0.234 0.233 0.264
Expression system: Escherichia coli BL21(DE3)