2eli

Solution NMR

Solution structure of the second Phorbol esters/diacylglycerol binding domain of human Protein kinase C alpha type

Released:
Source organism: Homo sapiens
Entry authors: Tochio N, Koshiba S, Saito K, Tomizawa T, Watanabe S, Harada T, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C alpha type Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.29 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P17252 (Residues: 93-169; Coverage: 12%)
Gene names: PKCA, PRKACA, PRKCA
Sequence domains: Phorbol esters/diacylglycerol binding domain (C1 domain)
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided