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Design of Disulfide-linked Thioredoxin Dimers and Multimers Through Analysis of Crystal Contacts

Source organism: Escherichia coli
Biochemical function: DNA polymerase processivity factor activity
Biological process: cell redox homeostasis
Cellular component: cytosol

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00085
Domain description: Thioredoxin
Occurring in:
  1. Thioredoxin 1
The deposited structure of PDB entry 2eiq contains 2 copies of Pfam domain PF00085 (Thioredoxin) in Thioredoxin 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013766
Domain description: Thioredoxin domain
Occurring in:
  1. Thioredoxin 1
IPR005746
Domain description: Thioredoxin
Occurring in:
  1. Thioredoxin 1
IPR017937
Domain description: Thioredoxin, conserved site
Occurring in:
  1. Thioredoxin 1
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. Thioredoxin 1

Structure domain

CATH CATH domain
3.40.30.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Glutaredoxin
Homology: Glutaredoxin
Occurring in:
  1. Thioredoxin 1
The deposited structure of PDB entry 2eiq contains 2 copies of CATH domain 3.40.30.10 (Glutaredoxin) in Thioredoxin 1. Showing 1 copy in chain A.

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