2e59

X-ray diffraction
2.21Å resolution

Crystal structure of human MD-2 in complex with lipid IVa

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lymphocyte antigen 96 Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.59 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q9Y6Y9 (Residues: 17-160; Coverage: 100%)
Gene names: ESOP1, LY96, MD2
Structure domains: Immunoglobulin-like

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P41212
Unit cell:
a: 52.795Å b: 52.795Å c: 110.889Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.263
Expression system: Komagataella pastoris