Function and Biology

Crystal structure of Sulfolobus tokodaii hexokinase in the apo form

Source organism: Sulfurisphaera tokodaii
Biochemical function: transferase activity
Biological process: carbohydrate phosphorylation
Cellular component: not assigned

EC 2.7.1.1: Hexokinase

Reaction catalysed:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Systematic name:
ATP:D-hexose 6-phosphotransferase
Alternative Name(s):
  • ATP-dependent hexokinase
  • Glucose ATP phosphotransferase
  • Hexokinase (phosphorylating)
  • Hexokinase D
  • Hexokinase type I
  • Hexokinase type II
  • Hexokinase type III
  • Hexokinase type IV
  • Hexokinase type IV (glucokinase)
  • Hexokinase type IV glucokinase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01869
Domain description: BadF/BadG/BcrA/BcrD ATPase family
Occurring in:
  1. ATPase BadF/BadG/BcrA/BcrD type domain-containing protein
The deposited structure of PDB entry 2e2n contains 2 copies of Pfam domain PF01869 (BadF/BadG/BcrA/BcrD ATPase family) in ATPase BadF/BadG/BcrA/BcrD type domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. ATPase BadF/BadG/BcrA/BcrD type domain-containing protein
IPR002731
Domain description: ATPase, BadF/BadG/BcrA/BcrD type
Occurring in:
  1. ATPase BadF/BadG/BcrA/BcrD type domain-containing protein

Structure domain

CATH CATH domain
3.30.420.40
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Nucleotidyltransferase; domain 5
Occurring in:
  1. ATPase BadF/BadG/BcrA/BcrD type domain-containing protein
The deposited structure of PDB entry 2e2n contains 4 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in ATPase BadF/BadG/BcrA/BcrD type domain-containing protein. Showing 2 copies in chain A.