› 2dvf

X-ray diffraction
2.74Å resolution

Crystals of peanut lectin grown in the presence of GAL-ALPHA-1,3-GAL-BETA-1,4-GAL

Released:
DOI: 10.2210/pdb2dvf/pdb
PDB entry 2dvf coloured by chain, front view.
PDB entry 2dvf coloured by chain, side view.
PDB entry 2dvf coloured by chain, top view.
Source organism: Arachis hypogaea
Primary publication:
Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin.
Natchiar SK, Srinivas O, Mitra N, Surolia A, Jayaraman N, Vijayan M
Acta Crystallogr D Biol Crystallogr 62 1413-21 (2006)
PMID: 17057347

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136281 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galactose-binding lectin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 236 amino acids
Theoretical weight: 25.21 KDa
Source organism: Arachis hypogaea
UniProt:
  • Canonical: P02872 (Residues: 24-259; Coverage: 94%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:
Ligand CA 4 x CA
Ligand MN 4 x MN
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 125.81Å b: 124.06Å c: 75.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.263

Quick links

Citations

3 review citations

Alpha-Gal detectors in xenotransplantation research: a word of caution.
Naso et al. (2012)
2 more

1 mention without citation

Design and characterization of high-affinity synthetic peptides as bioreceptors for diagnosis of cutaneous leishmaniasis.
Prada et al. (2021)