X-ray diffraction
2.5Å resolution

The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Sodium/calcium exchanger 1 Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 16.69 KDa
Source organism: Canis lupus familiaris
Expression system: Escherichia coli
  • Canonical: P23685 (Residues: 402-541; Coverage: 15%)
Gene names: NCX1, SLC8A1
Sequence domains: Calx-beta domain
Structure domains: Immunoglobulin-like

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P21212
Unit cell:
a: 59.624Å b: 45.524Å c: 57.269Å
α: 90° β: 90° γ: 90°
R R work R free
0.225 0.222 0.284
Expression system: Escherichia coli