2dob

X-ray diffraction
2Å resolution

Crystal Structure of Human Saposin A

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structures of saposins A and C.
Protein Sci. 15 1849-57 (2006)
PMID: 16823039

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saposin-A Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07602 (Residues: 58-140; Coverage: 16%)
Gene names: GLBA, PSAP, SAP1
Sequence domains:
Structure domains: Saposin-like

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P21212
Unit cell:
a: 45.68Å b: 50.04Å c: 33.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.218 0.267
Expression system: Escherichia coli