› 2dez

Solution NMR

Structure of human PYY

Released:
DOI: 10.2210/pdb2dez/pdb
PDB entry 2dez coloured by chain, ensemble of 20 models, front view.
PDB entry 2dez coloured by chain, ensemble of 20 models, side view.
PDB entry 2dez coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR.
Nygaard R, Nielbo S, Schwartz TW, Poulsen FM
Biochemistry 45 8350-7 (2006)
PMID: 16819834

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide YY Chain: A
Molecule details ›
Chain: A
Length: 37 amino acids
Theoretical weight: 4.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10082 (Residues: 29-64; Coverage: 52%)
Gene name: PYY
Sequence domains: Pancreatic hormone peptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

5 review citations

Neuropeptide Y Y2 receptor in health and disease.
Parker et al. (2008)
4 more

2 mentions without citation

Non-specific binding and general cross-reactivity of Y receptor agonists are correlated and should importantly depend on their acidic sectors.
Parker et al. (2011)
1 more