2dbj

Solution NMR

Solution structures of the fn3 domain of human Proto-oncogene tyrosine-protein kinase MER precursor

Released:
Source organism: Homo sapiens
Entry authors: Sato M, Tochio N, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Mer Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.01 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q12866 (Residues: 373-483; Coverage: 11%)
Gene names: MER, MERTK
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: torsion angle dynamics
Chemical shifts: BMR10300  
Expression system: Not provided